In the News: UVA Highlights First-in-Human Trial of hCitH3-mAb for Sepsis-Induced ARDS

As recently reported by the University of Virginia (link), a first-in-human clinical trial has begun evaluating hCitH3-mAb, a novel monoclonal antibody therapy targeting sepsis-induced acute respiratory distress syndrome (ARDS). Sepsis and ARDS remain leading causes of mortality in intensive care units, with limited treatment options beyond supportive care. The investigational antibody was developed to neutralize…

HTIC Receives FDA Clearance to Begin First-in-Human Trials for Novel Anti-NETosis Antibody

HTIC, Inc. is proud to announce a significant milestone in its therapeutic pipeline. The company recently submitted an Investigational New Drug (IND) application to the U.S. Food and Drug Administration for its first-in-class humanized monoclonal antibody designed to address NETosis-mediated immune dysregulation in human disease. On November 19, 2025, HTIC received the FDA’s “safe to…